30 April 2020
10:00 AM - 11:30 PM
Taha Morshedzadeh

Internal KCN: Potentials evoked by DBS at the STN

We will explore DBS in Parkinson's Disease, with the goal of devising a simple-to-implement algorithm for closed-loop control.

(Optional) Readings:

  1. Fleming, J. E., Dunn, E. & Lowery, M. M. Simulation of Closed-Loop Deep Brain Stimulation Control Schemes for Suppression of Pathological Beta Oscillations in Parkinson’s Disease. Front. Neurosci. 14, (2020). https://doi.org/10.3389/fnins.2020.00166
  2. Kumaravelu, K., Oza, C. S., Behrend, C. E., & Grill, W. M. (2018). Model-based deconstruction of cortical evoked potentials generated by subthalamic nucleus deep brain stimulation. Journal of Neurophysiology, 120(2), 662–680. https://doi.org/10.1152/jn.00862.2017
  3. Schmidt, S. L., Peters, J. J., Turner, D. A., & Grill, W. M. (2020). Continuous deep brain stimulation of the subthalamic nucleus may not modulate beta bursts in patients with Parkinson’s disease. Brain Stimulation, 13(2), 433–443. https://doi.org/10.1016/j.brs.2019.12.008