Krembil Computational Neuroscience

Krembil Computational Neuroscience

.... it is unclear where the inflection point describing model complexity and increased understanding lies.

Gjorgjieva et al. (Current Opinion in Neurobiology, 2016)

The first thing to do is to clearly state the goal of the modeling...

Shou et al. (eLife, 2015)

Because science starts with human interactions.... we must hope for people with different cultures, expertise, perspectives and footwear to leave their prejudices at the door and learn to appreciate each others` strengths...

G. Laurent (Nature Neuroscience, 2000)

Simulation neuroscience is a catalyst for experimental neuroscience, not a replacement.

H. Markram (Neuroscience News and Research, 2020)

Global understanding, when it comes, will likely take the form of highly diverse panels loosely stitched together into a patchwork quilt

Churchland and Abbott (Nature Neuroscience, 2016)

...we should read the words on the page or screen, not the words in our head as we read papers by other scientists and try to make sure that our own papers capture our intent.

E Marder (eLife, 2020)

Neither ignore the details nor be consumed by them... the balance is the challenge in advancing our understanding.

Skinner and Mulloney (Current Opinion in Neurobiology, 1998)

The future will depend on stronger quantitative understanding in our experimental community and better biology intuition in our theory community.

E Marder (PLoS Biology, 2015)

Mathematics is biology`s next microscope.

JE Cohen (PLoS Biology, 2004)

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Recent and Upcoming

KCNhub members Drs. Luka Milosevic and Taufik Valiante and colleague receive CFI JELF Award
Congratulations! Drs. Luka Milosevic, Suneil Kalia and Taufik Valiante are one of five UHN research teams to have received Canada Foundation for Innovation’s John R. Evans Leaders Fund (JELF) for research infrastructure.
Internal KCN: Novel Construction of Biophysical Computational Model of Basal Ganglia
Lab Meeting
4 October 2022
09:30 - 11:00 AM
Virtually via Zoom
David Crompton
KCNhub members Drs. Afroditi Talidou and Jeremie Lefebvre and collaborators publish new paper
The authors studied the effects of activity-dependent myelination (ADM) on network activity and information transmission in the brain. They found that ADM implements a homeostatic gain control mechanism that enhances neural firing rates and correlations through the temporal coordination of action potentials as axon lengths increase. Moreover, ADM enhances information transmission under various types of time-varying stimuli. These results highlight the role of ADM in shaping neural activity and communication.
Upcoming KCN Seminar
18 October 2022
09:30 - 11:30 AM
Jesse Gillis (Toronto)
Krembil Neuroinformatics Talk of interest by Dr. Bengi Baran
The following talk may be of interest to KCNhubbers and the computational neuroscience community. It continues a speaker series at the Krembil Center for Neuroinformatics (KCNI) at CAMH.
Internal KCN: Journal Club Presentation
Lab Meeting
1 November - 20 September 2022
09:30 - 11:00 AM
In person or zoom - TBD
Frances Skinner


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