The role of astrocytes in stress-induced cognitive dysfunction

Abstract: Early-life stress, i.e. stressful experiences that occur during postnatal development, can have lifelong consequences on stress susceptibility and behaviour. While much has been discovered regarding the effects of early-life stress (ELS) on neuronal function, little is known about the contribution of non-neuronal brain cells to the cellular, network, and behavioural adaptations following ELS. In this seminar I will discuss our latest findings investigating the long-term impact of ELS on astrocyte structure, function, and how these glia contribute to cognitive impairments in adult mice

Biosketch: Ciaran Murphy-Royal is an assistant professor in the Department of Neuroscience at the Université de Montréal. His lab at the University of Montreal Hospital Research Centre (CRCHUM), studies how stress influences brain structure and function. His team focuses on a star-shaped brain cells, called astrocytes, which are known to sculpt neuronal activity and plasticity. Deciphering how astrocyte-neuron interactions are perturbed by stress, their research program aims to expanding our understanding of the neurobiology of stress linking cellular and behavioural scales.

See below for link to join via zoom:

Topic: KCN Event: Ciaran Murphy-Royal

Time: Nov 30, 2021 10:00 Eastern Time (US and Canada)

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https://utoronto.zoom.us/j/86767781348

Meeting ID: 867 6778 1348

Passcode: 645129