Krembil Computational Neuroscience
Krembil Computational Neuroscience
Harnessing mathematical modeling and engineering to bridge theory and practice in neural health and diseases
KCNhub Mission Statement
Because science starts with human interactions.... we must hope for people with different cultures, expertise, perspectives and footwear to leave their prejudices at the door and learn to appreciate each others` strengths...
G. Laurent (Nature Neuroscience, 2000)
The future will depend on stronger quantitative understanding in our experimental community and better biology intuition in our theory community.
E Marder (PLoS Biology, 2015)
News and Info
30Dec
KCNhub members Spandan Sengupta, Drs. Frances Skinner and Jeremie Lefebvre and KCNhub alumnus Dr. Afroditi Talidou publish new paper
There are many different types of inhibitory cells in our brains that are differentially affected in disease. Concomitantly, coupled rhythms change in particular ways with disease. To help understand cell-type-specific changes in coupled rhythms, we develop a mathematical network model that is both respective of the cell type and also amenable to analyses. We focus on theta-gamma coupled rhythms in the hippocampus and include three different inhibitory cell types in our model circuits. By combining a theoretical analysis and numerical explorations, we find distinct contributions of these inhibitory cell types to coupled rhythms and predict motifs that are essential for the expression of theta-gamma coupled rhythms. Moving forward, we can leverage our model insights to help unravel cell-type contributions in disease states.
31Dec
KCNhub member Dr. Frances Skinner retires at the end of 2024
Frances will transition to Emerita Scientist in the new year after formally retiring at the end of 2024. She will continue as an active member of KCNhub!
31Dec
EMBO Workshop on Astrocytes: From Molecules to Systems
KCNhub member Maurizio De Pittà will be a speaker at this EMBO Workshop which is the first international meeting dedicated to astrocytes. It will take place at the Venice International University on San Servolo Island in Venice (Italy) on April 14–18, 2025.
14Jan
EMBO Course on Quantifying Astrocyte Physiology by Models from Genome to Circuits
KCNhub member Maurizio De Pittà is speaker and curator for this EMBO Meeting Satellite event on April 10–11, 2025 at the University of Padua, Padua, Italy
3Feb
Fields Institute Thematic Program on the Mathematics of Neuroscience
KCNhub and KCNI members (Griffiths, Lefebvre, Skinner) are on the organizing committee for this program that will take place in 2025 (July to December).
Recent and Upcoming
7Jan
Internal KCN: Journal Club - targeted tFUS and BCI
7 January 2025
13:00 - 14:30 PM
4KD503
Jathushan Kaetheeswaran
14Jan
Internal KCN: Journal Club - optimized ultrasound neuromodulation
14 January 2025
13:00 - 14:30 PM
4KD503
Zoe Paraskevopoulos
21Jan
Internal KCN: Journal Club
21 January 2025
13:00 - 14:30 PM
4KD503
Spandan Sengupta
28Jan
Internal KCN: Journal Club
28 January 2025
13:00 - 14:30 PM
4KD503
David Crompton
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